SCHEMBL9450002

SCHEMBL9450002

O=C(O)CCCCON=C1c2ccccc2CCC1n1ccnc1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 19/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9450000 1.00 TBXA2R (0.48) TBXA2R
SCHEMBL9449662 0.88 TBXA2R (0.47) TBXA2R
SCHEMBL9449760 0.86 TBXA2R (0.46) TBXA2R
SCHEMBL9449754 0.86 TBXA2R (0.46) TBXA2R
SCHEMBL9449763 0.86 TBXA2R (0.46) TBXA2R
SCHEMBL9449551 0.83 TBXA2R (0.38) TBXA2R
SCHEMBL9449627 0.81 TBXA2R (0.43) TBXA2R
SCHEMBL9449628 0.81 TBXA2R (0.43) TBXA2R
SCHEMBL9449542 0.80 TBXA2R (0.43) TBXA2R
SCHEMBL9449546 0.80 TBXA2R (0.43) TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246956-A N-IMIDAZOLYL DERIVATIVES OF SUBSTITUTED ALKOXYIMINO TETRAHYDRONAPHTHALENES AND CHROMANS HAVING ANTITHROMBOXANE A2 ACTIVITY FARMITALIA CARLO ERBA S.R.L. (IT) 1993-09-21 US claimed
EP-0499444-A1 N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans PHARMACIA S.p.A. (IT) 1992-08-19 EP claimed
US-5246956-A N-IMIDAZOLYL DERIVATIVES OF SUBSTITUTED ALKOXYIMINO TETRAHYDRONAPHTHALENES AND CHROMANS HAVING ANTITHROMBOXANE A2 ACTIVITY FARMITALIA CARLO ERBA S.R.L. (IT) 1993-09-21 US disclosed
EP-0499444-A1 N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans PHARMACIA S.p.A. (IT) 1992-08-19 EP disclosed