Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449763 | 1.00 | TBXA2R (0.46) | TBXA2RCYP19A1TBXAS1 | |
| SCHEMBL9449760 | 1.00 | TBXA2R (0.46) | TBXA2RCYP19A1TBXAS1 | |
| SCHEMBL9450000 | 0.86 | TBXA2R (0.48) | TBXA2R | |
| SCHEMBL9450002 | 0.86 | TBXA2R (0.48) | TBXA2R | |
| SCHEMBL9449662 | 0.77 | TBXA2R (0.47) | TBXA2RTBXAS1 | |
| SCHEMBL10859613 | 0.75 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL9449672 | 0.72 | KDM4E (0.37) | TBXA2RCYP19A1 | |
| SCHEMBL9449551 | 0.72 | TBXA2R (0.38) | TBXA2R | |
| SCHEMBL9449627 | 0.71 | TBXA2R (0.43) | TBXA2R | |
| SCHEMBL9449628 | 0.71 | TBXA2R (0.43) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246956-A | N-IMIDAZOLYL DERIVATIVES OF SUBSTITUTED ALKOXYIMINO TETRAHYDRONAPHTHALENES AND CHROMANS HAVING ANTITHROMBOXANE A2 ACTIVITY | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-09-21 | — | — | US | claimed |
| EP-0499444-A1 | N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans | PHARMACIA S.p.A. (IT) | 1992-08-19 | — | — | EP | claimed |
| US-5246956-A | N-IMIDAZOLYL DERIVATIVES OF SUBSTITUTED ALKOXYIMINO TETRAHYDRONAPHTHALENES AND CHROMANS HAVING ANTITHROMBOXANE A2 ACTIVITY | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-09-21 | — | — | US | disclosed |
| EP-0499444-A1 | N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans | PHARMACIA S.p.A. (IT) | 1992-08-19 | — | — | EP | disclosed |