Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450073 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPK1DRD3DRD2MAPT | |
| SCHEMBL10532562 | 0.71 | DRD3 (0.45) | ALDH1A1MAPK1DRD3DRD2MAPT | |
| SCHEMBL10531165 | 0.71 | HTR2B (0.41) | ALDH1A1MAPK1DRD3DRD2MAPT | |
| Hydrochloric Acid SCHEMBL10531205 | 0.70 | DRD3 (0.44) | ALDH1A1MAPK1DRD3DRD2MAPT | |
| SCHEMBL9450209 | 0.69 | HTR2B (0.41) | ALDH1A1KDM4ELMNA | |
| SCHEMBL10528728 | 0.68 | HTR2B (0.41) | ALDH1A1MAPK1DRD3DRD2MAPT | |
| SCHEMBL30782284 | 0.67 | MAPK1 (0.57) | ALDH1A1MAPK1MAPTKDM4ENPC1 | |
| SCHEMBL27145774 | 0.67 | MAPK1 (0.57) | ALDH1A1MAPK1MAPTKDM4ENPC1 | |
| SCHEMBL9812347 | 0.67 | KDM4E (0.41) | ALDH1A1MAPK1MAPTKDM4ENPC1 | |
| SCHEMBL30583381 | 0.67 | BRD4 (0.55) | ALDH1A1MAPK1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204364-A | Selective inhibition of thromboxane A2; anticholesterol agents treating nephrosis, hyperlipidemia | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1993-04-20 | — | — | US | disclosed |
| EP-0363789-B1 | N-IMIDAZOLYL-AND N-IMIDAZOLYL-METHYL DERIVATIVES OR SUBSTITUTED BICYCLIC COMPOUNDS | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-05-06 | — | — | EP | disclosed |
| EP-0363789-A1 | N-imidazolyl-and N-imidazolyl-methyl derivatives or substituted bicyclic compounds | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | disclosed |