SCHEMBL9450271

SCHEMBL9450271

O=C1OC(=O)C2C(F)=CCCC12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738566 0.81 FNTA (0.30)
SCHEMBL9450278 0.77
SCHEMBL9450263 0.77
SCHEMBL9363135 0.69
SCHEMBL7189081 0.67 KDM4E (0.30)
SCHEMBL7189076 0.67 KDM4E (0.30)
SCHEMBL7189088 0.67 KDM4E (0.30)
SCHEMBL6882262 0.64 KDM4E (0.34)
SCHEMBL12428071 0.63 KDM4E (0.46)
SCHEMBL22300607 0.63 KDM4E (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330219-B1 Preparation of substituted phthalic anhydride OCCIDENTAL CHEM CO (US) 1993-12-29 EP disclosed
US-5233054-A Dehydrogenating, brominating the halogen substituted hexa- or tetra-hydrophthalic anhydride in the presence of free radical catalysts OCCIDENTAL CHEMICAL CORPORATION (US) 1993-08-03 US disclosed
US-5206391-A Reacting BR2 with halohydrophthalic anhydride, reacting HBR with CL2 to regenerate bromine OCCIDENTAL CHEMICAL CORPORATION (US) 1993-04-27 US disclosed
US-5049682-A Halogenation OCCIDENTAL CHEMICAL CORPORATION (US) 1991-09-17 US disclosed
US-5003088-A Method for the preparation of halophthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-26 US disclosed
EP-0417691-A2 Process for the preparation of halophthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-20 EP disclosed
US-4978760-A Preparation of halogen substituted phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-12-18 US disclosed
EP-0338215-A2 Process for the preparation of halogen-substituted phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-25 EP disclosed
EP-0334049-A2 Process for the preparation of halogen-substituted phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-09-27 EP disclosed
EP-0330219-A2 Preparation of substituted phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-30 EP disclosed