Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450341 | 1.00 | TDP1 (0.40) | TDP1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11744216 | 0.97 | TDP1 (0.42) | TDP1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11744239 | 0.97 | TDP1 (0.42) | TDP1ADH1BADH1CADH1AADH4 | |
| SCHEMBL29860701 | 0.84 | ADH1B (0.36) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL9719598 | 0.77 | ADH1B (0.34) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL28216071 | 0.76 | ADH1B (0.37) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL10366842 | 0.75 | ADH1B (0.33) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8769980 | 0.75 | ADH1B (0.33) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL10768126 | 0.75 | ADH1B (0.33) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL10768135 | 0.75 | ADH1B (0.33) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254697-A | Process for the preparation of haloalkyllactones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |