Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.44 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872221 | 0.95 | DPP4 (0.52) | DPP4DPP8RENACEMALT1 | |
| SCHEMBL9450494 | 0.92 | EPHA2 (0.48) | RENMALT1NMUR2NMUR1EPHA2 | |
| SCHEMBL9450499 | 0.89 | EPHA2 (0.50) | DPP4DPP8RENMALT1NMUR2 | |
| SCHEMBL1370330 | 0.88 | MAPK8 (0.51) | RENMALT1NMUR2NMUR1EPHA2 | |
| SCHEMBL9450487 | 0.87 | CMA1 (0.47) | DPP4DPP8ACEMALT1NMUR2 | |
| SCHEMBL11063141 | 0.86 | CTRB1 (0.57) | CTRB1 | |
| SCHEMBL11063150 | 0.86 | CTRB1 (0.57) | CTRB1 | |
| SCHEMBL29388202 | 0.86 | PREP (0.51) | DPP4DPP8ACEDPP7DPP9 | |
| SCHEMBL18619636 | 0.85 | MALT1 (0.55) | DPP4DPP8RENACEMALT1 | |
| SCHEMBL7402728 | 0.83 | ACE (0.55) | DPP4DPP8RENACEDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212287-A | Multistage synthesis of oligopeptides with protection of side groups then deprotection after reaction | IMMUNETECH PHARMACEUTICALS, INC. (US) | 1993-05-18 | — | — | US | disclosed |