Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450639 | 1.00 | PRSS1 (0.39) | PRSS1CTRCF2FAAHPOLB | |
| SCHEMBL9450611 | 1.00 | PRSS1 (0.39) | PRSS1CTRCF2FAAHPOLB | |
| SCHEMBL11220219 | 0.87 | PRSS1 (0.36) | PRSS1CTRCF2FAAHPOLB | |
| SCHEMBL576642 | 0.87 | POLB (0.41) | PRSS1CTRCF2FAAHPOLB | |
| SCHEMBL11221919 | 0.87 | PRSS1 (0.36) | PRSS1CTRCF2FAAHPOLB | |
| SCHEMBL11033189 | 0.83 | PRSS1 (0.33) | PRSS1CTRCF2FAAHPOLB | |
| SCHEMBL5936331 | 0.80 | HTT (0.52) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL3658589 | 0.80 | ALDH1A1 (0.49) | POLBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3660316 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL14883094 | 0.78 | KMT2A (0.42) | PRSS1CTRCF2FAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559789-A1 | PROCESS FOR THE PREPARATION OF $g(a)-ALKYL LACTONES | HENKEL CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5231192-A | Reacting an a-acyl lactone, an aldehyde and an alkali metal hydroxide; hydrogenation | HENKEL CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1992009590-A1 | PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES | HENKEL CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| US-4980342-A | Process for the preparation of α-alkyl lactones | HENKEL CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |