Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | CASP1 | P29466 | 4/20 | 0.47 |
| ▸ | CASP7 | P55210 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307793 | 0.83 | CDK5 (0.54) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9450598 | 0.79 | KDM4E (0.53) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9450628 | 0.77 | KDM4E (0.52) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL10952664 | 0.77 | KDR (0.48) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL11809624 | 0.77 | BCL2 (0.50) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9450619 | 0.75 | KDM4E (0.50) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL17617827 | 0.75 | KMT2A (0.56) | KDM4EALDH1A1HPGDHTTPOLB | |
| SCHEMBL13256237 | 0.74 | CDK5 (0.57) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL17617825 | 0.74 | TYMS (0.51) | KDM4EALDH1A1HPGDPOLBUSP2 | |
| SCHEMBL9703135 | 0.73 | CDK5 (0.53) | CDK5CDK5R1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | claimed |