Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208006 | 0.89 | TSHR (0.44) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL8771858 | 0.86 | THRB (0.37) | TSHRTHRBALDH1A1TET2 | |
| SCHEMBL11701319 | 0.86 | FFAR3 (0.46) | TSHRTHRBFFAR3HDAC3HDAC1 | |
| SCHEMBL11027815 | 0.86 | TSHR (0.50) | TSHRTHRBALDH1A1DGKA | |
| SCHEMBL3423721 | 0.86 | THRB (0.47) | TSHRTHRBFFAR3HDAC3HDAC1 | |
| SCHEMBL3476011 | 0.84 | TSHR (0.44) | TSHRTHRBFFAR3HDAC3HDAC1 | |
| SCHEMBL7758811 | 0.82 | — | — | |
| SCHEMBL5851844 | 0.81 | TSHR (0.53) | TSHRTHRBFFAR3HDAC3HDAC1 | |
| SCHEMBL17818 | 0.81 | — | — | |
| SCHEMBL8736372 | 0.80 | CHRM2 (0.36) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537338-A1 | THERMALLY STABLE COMPOSITIONS AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING THE SAME. | LUBRIZOL CORP (US) | 1993-04-21 | — | — | EP | disclosed |