Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | ARG2 | P78540 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361435 | 0.85 | ARG1 (0.41) | ARG1ARG2TSHRSMN1; SMN2HIF1A | |
| SCHEMBL26696026 | 0.79 | KDM4E (0.50) | KDM4EPOLBTSHRSMN1; SMN2HIF1A | |
| SCHEMBL7653153 | 0.78 | ARG1 (0.62) | ARG1ARG2TSHRSMN1; SMN2HIF1A | |
| SCHEMBL17667387 | 0.76 | KDM4E (0.57) | KDM4EPOLBTSHRSMN1; SMN2HIF1A | |
| SCHEMBL17667388 | 0.76 | KDM4E (0.57) | KDM4EPOLBTSHRSMN1; SMN2HIF1A | |
| SCHEMBL7936507 | 0.76 | KDM4E (0.57) | KDM4EPOLBTSHRSMN1; SMN2HIF1A | |
| SCHEMBL9629603 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ANPC1RAB9AALDH1A1 | |
| SCHEMBL3547434 | 0.74 | KDM4E (0.55) | KDM4EPOLBTSHRSMN1; SMN2HIF1A | |
| SCHEMBL8839506 | 0.74 | KDM4E (0.55) | KDM4EPOLBTSHRSMN1; SMN2HIF1A | |
| SCHEMBL27427480 | 0.74 | KDM4E (0.56) | KDM4EPOLBTSHRSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182370-A | Diagnostic NMR imaging | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1993-01-26 | — | — | US | disclosed |
| US-4980502-A | For nuclear magnetic resonance imaging | BRACCO INDUSTRIA CHIMICA, S.P.A. (IT) | 1990-12-25 | — | — | US | disclosed |
| EP-0230893-B1 | PARAMAGNETIC CHELATES | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4916246-A | Paramagnetic chelates useful for NMR imaging | BRACCO CHIMICA S.P.A. (IT) | 1990-04-10 | — | — | US | disclosed |
| EP-0230893-A2 | Paramagnetic chelates | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1987-08-05 | — | — | EP | disclosed |