Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenoxyethanol SCHEMBL5769895 | 0.92 | ALDH1A1 (0.79) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Sulfamate SCHEMBL9451480 | 0.91 | ALDH1A1 (0.59) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL27476573 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL15708 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL167128 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL9349725 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL11328286 | 0.84 | ALDH1A1 (0.86) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL3838823 | 0.84 | ALDH1A1 (0.86) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL18074838 | 0.83 | ALDH1A1 (0.95) | ALDH1A1RECQLGAATAAR1KCNA3 | |
| Phenoxyethanol SCHEMBL8837237 | 0.83 | ALDH1A1 (0.95) | ALDH1A1RECQLGAATAAR1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | claimed |
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |