Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169598 | 0.83 | BRD4 (0.44) | BRD4ALDH1A1MAPK1HSD17B10PARP1 | |
| SCHEMBL19423620 | 0.76 | USP2 (0.51) | BRD4HSD17B10KMT2AMEN1CREBBP | |
| SCHEMBL24508983 | 0.74 | BRD4 (0.44) | BRD4ALDH1A1MAPK1HSD17B10KMT2A | |
| SCHEMBL30336298 | 0.74 | BRD4 (0.44) | BRD4ALDH1A1MAPK1HSD17B10KMT2A | |
| SCHEMBL19410329 | 0.73 | BRD4 (0.43) | BRD4ALDH1A1MAPK1HSD17B10KMT2A | |
| SCHEMBL19432962 | 0.72 | TP53 (0.48) | BRD4ALDH1A1MAPK1HSD17B10KMT2A | |
| SCHEMBL19419343 | 0.72 | BRD4 (0.43) | BRD4ALDH1A1MAPK1HSD17B10PARP1 | |
| SCHEMBL5518583 | 0.71 | KMT2A (0.65) | BRD4ALDH1A1MAPK1HSD17B10KMT2A | |
| SCHEMBL3249363 | 0.70 | PARP1 (0.62) | ALDH1A1MAPK1HSD17B10PARP1KMT2A | |
| SCHEMBL26310974 | 0.69 | PARP1 (0.53) | MAPK1HSD17B10PARP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |