Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26311050 | 0.86 | L3MBTL1 (0.53) | PARP1MAPK1L3MBTL1TP53POLB | |
| SCHEMBL26310973 | 0.83 | PARP1 (0.49) | PARP1MAPK1L3MBTL1TP53POLB | |
| SCHEMBL11831795 | 0.82 | HSD17B10 (0.61) | PARP1MAPK1L3MBTL1TP53POLB | |
| SCHEMBL6997788 | 0.82 | PARP1 (0.64) | PARP1MAPK1TP53POLBSMN1; SMN2 | |
| SCHEMBL3077917 | 0.81 | MAPK1 (0.49) | PARP1MAPK1L3MBTL1TP53POLB | |
| SCHEMBL23571859 | 0.81 | USP2 (0.65) | TP53USP2GAAHSD17B10TSHR | |
| SCHEMBL29823082 | 0.81 | USP2 (0.65) | TP53USP2GAAHSD17B10TSHR | |
| SCHEMBL23534259 | 0.79 | L3MBTL1 (0.49) | PARP1MAPK1L3MBTL1TP53USP2 | |
| SCHEMBL7003159 | 0.79 | PARP1 (0.74) | PARP1MAPK1L3MBTL1TP53POLB | |
| SCHEMBL532921 | 0.77 | USP2 (0.48) | PARP1MAPK1L3MBTL1TP53USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |