Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.61 |
| ▸ | RXRA | P19793 | 3/20 | 0.61 |
| ▸ | RXRB | P28702 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | RXRG | P48443 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750639 | 1.00 | HSD17B10 (0.61) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11753276 | 0.95 | HSD17B10 (0.64) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11752729 | 0.91 | GAA (0.70) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11745584 | 0.89 | HSD17B10 (0.68) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11752392 | 0.89 | RXRA (0.54) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11750019 | 0.89 | RXRA (0.54) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11755875 | 0.89 | RXRA (0.54) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11751481 | 0.89 | RXRA (0.54) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11752234 | 0.89 | RXRA (0.54) | HSD17B10CYP2C19CYP1A2POLBNR4A2 | |
| SCHEMBL11749898 | 0.89 | RXRA (0.54) | HSD17B10CYP2C19CYP1A2POLBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434034-A1 | Oxazole derivatives | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | claimed |
| US-5262540-A | FOR INHIBITION OF BLOOD PLATELET AGGREGATION IN MAMMALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0434034-A1 | Oxazole derivatives | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |