Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22266169 | 0.93 | ALDH1A1 (0.59) | HDAC1HDAC2HRH3ALDH1A1RECQL | |
| SCHEMBL30230040 | 0.93 | ALDH1A1 (0.59) | HDAC1HDAC2HRH3ALDH1A1RECQL | |
| SCHEMBL5321573 | 0.92 | FFAR4 (0.58) | HDAC1HDAC2HRH3ALDH1A1RECQL | |
| SCHEMBL4320104 | 0.89 | ALDH1A1 (0.69) | HDAC1HDAC2HRH3ALDH1A1RECQL | |
| SCHEMBL8928364 | 0.85 | PRSS1 (0.55) | ALDH1A1RECQLKCNA3 | |
| SCHEMBL10671455 | 0.84 | HRH3 (0.60) | HDAC1HDAC2HRH3HDAC3HDAC4 | |
| SCHEMBL10676504 | 0.84 | HRH3 (0.60) | HDAC1HDAC2HRH3HDAC3HDAC4 | |
| SCHEMBL10676185 | 0.84 | HRH3 (0.60) | HDAC1HDAC2HRH3HDAC3HDAC4 | |
| SCHEMBL10681293 | 0.84 | HRH3 (0.60) | HDAC1HDAC2HRH3HDAC3HDAC4 | |
| SCHEMBL10683208 | 0.84 | HRH3 (0.60) | HDAC1HDAC2HRH3HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177108-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5077315-A | Treatment of HIV virus | MERRELL DOW PHARMACEUTICALS (US) | 1991-12-31 | — | — | US | disclosed |
| US-4939173-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0373587-A2 | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | disclosed |