Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQLE | Q14534 | 20/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454160 | 1.00 | SQLE (0.61) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL9454638 | 0.92 | SQLE (0.60) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL9454628 | 0.92 | SQLE (0.60) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL9454686 | 0.92 | SQLE (0.60) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL9454619 | 0.92 | SQLE (0.60) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL9454627 | 0.92 | SQLE (0.60) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL9454643 | 0.91 | SQLE (0.61) | SQLE | |
| SCHEMBL9454635 | 0.91 | SQLE (0.61) | SQLE | |
| SCHEMBL9454397 | 0.91 | SQLE (0.61) | SQLE | |
| SCHEMBL9454835 | 0.91 | SQLE (0.61) | SQLE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |