SCHEMBL9454397

SCHEMBL9454397

COc1ccc(COc2cccc(CN(C)CC=CC#CC(C)(C)C)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SQLE Q14534 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454387 1.00 SQLE (0.61) SQLE
SCHEMBL9455058 1.00 SQLE (0.61) SQLE
Hydrochloric Acid SCHEMBL9454344 0.93 SQLE (0.58) SQLE
Hydrochloric Acid SCHEMBL9454338 0.93 SQLE (0.58) SQLE
SCHEMBL9454150 0.91 SQLE (0.61) SQLE
SCHEMBL9454160 0.91 SQLE (0.61) SQLE
Hydrochloric Acid SCHEMBL9454627 0.91 SQLE (0.60) SQLE
Hydrochloric Acid SCHEMBL9454619 0.91 SQLE (0.60) SQLE
Hydrochloric Acid SCHEMBL9454686 0.91 SQLE (0.60) SQLE
SCHEMBL9454635 0.90 SQLE (0.61) SQLE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US disclosed
EP-0318860-B1 SUBSTITUTED ALKYLAMINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-16 EP disclosed
EP-0318860-A2 Substituted alkylamine derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-06-07 EP disclosed