Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454561 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HPGDMEN1KMT2ACYP19A1 | |
| SCHEMBL3171270 | 0.91 | CYP19A1 (0.39) | MEN1KMT2ACYP19A1MAPTGAA | |
| SCHEMBL9349703 | 0.91 | CYP19A1 (0.39) | MEN1KMT2ACYP19A1MAPTGAA | |
| SCHEMBL31462867 | 0.91 | CYP19A1 (0.39) | MEN1KMT2ACYP19A1MAPTGAA | |
| SCHEMBL3171264 | 0.91 | CYP19A1 (0.39) | MEN1KMT2ACYP19A1MAPTGAA | |
| SCHEMBL9349700 | 0.91 | CYP19A1 (0.39) | MEN1KMT2ACYP19A1MAPTGAA | |
| SCHEMBL9349839 | 0.87 | MAPT (0.40) | ALDH1A1HPGDMEN1KMT2ACYP19A1 | |
| SCHEMBL9349828 | 0.87 | MAPT (0.40) | ALDH1A1HPGDMEN1KMT2ACYP19A1 | |
| SCHEMBL9454225 | 0.87 | CYP19A1 (0.41) | ALDH1A1HPGDMEN1KMT2ACYP19A1 | |
| SCHEMBL9353332 | 0.87 | CYP19A1 (0.41) | ALDH1A1HPGDMEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194389-A | PH indicators | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-16 | — | — | US | disclosed |