Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845977 | 0.94 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9455048 | 0.94 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9455177 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9454851 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9454425 | 0.91 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9455081 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9455134 | 0.86 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9135647 | 0.85 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9454831 | 0.85 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9454842 | 0.85 | AGTR1 (0.43) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198439-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5130318-A | Hypotensive agents and for treatment of congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-14 | — | — | US | disclosed |
| EP-0453210-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |