Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.60 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.60 |
| ▸ | PRKCI | P41743 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484231 | 0.93 | MKNK1 (0.68) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL4581739 | 0.93 | MKNK1 (0.68) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL1139185 | 0.87 | EPHX2 (0.59) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL16996659 | 0.81 | MKNK1 (0.70) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL9454544 | 0.80 | MKNK1 (0.55) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL9454416 | 0.80 | MKNK1 (0.55) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL9454404 | 0.80 | MKNK1 (0.55) | MKNK1MKNK2PRKCIEPHX2PRMT6 | |
| SCHEMBL5216350 | 0.80 | CHRNA7 (0.65) | MKNK1MKNK2EPHX2PRMT6BACE1 | |
| SCHEMBL4468765 | 0.80 | EPHX2 (0.64) | MKNK1MKNK2EPHX2PRMT6BACE1 | |
| SCHEMBL1130316 | 0.80 | EPHX2 (0.59) | MKNK1MKNK2PRKCIEPHX2PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0395768-A1 | SUBSTITUTED ALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |