Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243663 | 0.95 | DGKA (0.67) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL31620703 | 0.90 | DGKA (0.65) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL8431143 | 0.88 | TSHR (0.53) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL10423224 | 0.88 | TSHR (0.53) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL20960099 | 0.88 | DGKA (0.62) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL229572 | 0.87 | CYP3A4 (0.70) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL18204387 | 0.86 | DGKA (0.65) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL20960163 | 0.86 | DGKA (0.65) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL19553630 | 0.86 | DGKA (0.65) | CYP3A4TSHRATMTDP1DGKA | |
| SCHEMBL495006 | 0.85 | CYP3A4 (0.50) | CYP3A4TSHRATMTDP1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5253461-A | Fastener-free roofing system and method | TREMCO, INC. (US) | 1993-10-19 | — | — | US | claimed |
| US-5253461-A | Fastener-free roofing system and method | TREMCO, INC. (US) | 1993-10-19 | — | — | US | disclosed |