Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.65 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529521 | 1.00 | FFAR4 (0.69) | FFAR4FFAR1CYSLTR2CYSLTR1PTGER1 | |
| SCHEMBL27262058 | 0.89 | CYSLTR2 (0.68) | FFAR4FFAR1CYSLTR2CYSLTR1 | |
| SCHEMBL25170031 | 0.89 | CYSLTR2 (0.68) | FFAR4FFAR1CYSLTR2CYSLTR1 | |
| SCHEMBL9319505 | 0.88 | CYSLTR2 (0.73) | FFAR4FFAR1CYSLTR2CYSLTR1PTGER1 | |
| SCHEMBL28879347 | 0.85 | CYSLTR2 (0.55) | FFAR4FFAR1CYSLTR2CYSLTR1PTGER1 | |
| Toluene SCHEMBL7506822 | 0.85 | FFAR4 (0.73) | FFAR4FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL10435206 | 0.83 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL12086495 | 0.83 | LTB4R (0.63) | FFAR4FFAR1CYSLTR2CYSLTR1SCD | |
| Benzoic Acid SCHEMBL5273790 | 0.83 | FFAR4 (0.69) | FFAR4FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL25190974 | 0.83 | FFAR4 (1.00) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419610-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | claimed |
| US-5196570-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | claimed |
| EP-0419610-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS. | SCHERING AG (DE) | 1991-04-03 | — | — | EP | claimed |
| WO-1990011271-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-10-04 | — | — | WO | claimed |
| EP-0419610-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0419610-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS. | SCHERING AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| WO-1990011271-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-10-04 | — | — | WO | disclosed |