Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | HTT | P42858 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067838 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL21082987 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL17067839 | 0.85 | KDM4E (0.63) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL21082988 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL10071684 | 0.84 | KMT2A (0.58) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL18657298 | 0.84 | KMT2A (0.57) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL10071686 | 0.82 | MEN1 (0.69) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL17211883 | 0.82 | MEN1 (0.63) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL17211957 | 0.82 | MEN1 (0.57) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL684611 | 0.81 | MEN1 (0.71) | KMT2AMEN1MAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204311-A | Yellow colored coordination compounds of transition metals | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0531020-A1 | Ethanediimidic acid bis arylalkylidene)hydrazide | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |