Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.63 |
| ▸ | HTT | P42858 | 10/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19441434 | 0.88 | MEN1 (0.60) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL19441435 | 0.88 | MEN1 (0.60) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL21082988 | 0.87 | MEN1 (0.65) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL21082987 | 0.87 | MEN1 (0.65) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL17211957 | 0.85 | MEN1 (0.57) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL17067838 | 0.84 | MEN1 (0.65) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL10071684 | 0.84 | KMT2A (0.58) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL9458183 | 0.82 | KMT2A (0.62) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL10071686 | 0.82 | MEN1 (0.69) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL684611 | 0.81 | MEN1 (0.71) | MEN1KMT2AHTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783499-B2 | Quinoline derivatives and their applications | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2017-10-10 | — | — | US | disclosed |
| US-20150307453-A1 | NOVEL QUINOLINE DERIVATIVES AND THEIR APPLICATIONS | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307453-A1 | NOVEL QUINOLINE DERIVATIVES AND THEIR APPLICATIONS | MET, RAF1, RET | MEN1 54/4885KMT2A 1174/4885HTT 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.