SCHEMBL9458191

SCHEMBL9458191

CC(C)(C)CC(C(=O)Oc1ccc(C(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(O)c1)c1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.43
GAA P10253 1/20 0.43
XBP1 P17861 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NR1H4 Q96RI1 7/20 0.40
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
ESRRA P11474 2/20 0.37
HPGD P15428 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
PGR P06401 1/20 0.36
CYP2D6 P10635 1/20 0.36
SLC6A2 P23975 1/20 0.36
PDE4A P27815 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
HRH1 P35367 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9457940 0.91 HPGD (0.47) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL9458229 0.91 GAA (0.37) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL9458187 0.81 HPGD (0.41) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL9458194 0.80 NR1H4 (0.40) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL9457384 0.76 ALOX5 (0.41) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28876789 0.76 ATM (0.64) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL9458223 0.76 BCL2 (0.37) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL1871824 0.75 ATM (0.41) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL8744623 0.75 NR1H4 (0.51) ATMGAANR1H4POLBMAPT
SCHEMBL9457926 0.75 HPGD (0.52) GAAPOLBMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5274170-A Substituted benzophenone stabilizers CIBA-GEIGY CORPORATION (US) 1993-12-28 US claimed
US-5274170-A Substituted benzophenone stabilizers CIBA-GEIGY CORPORATION (US) 1993-12-28 US disclosed
US-5145766-A Benzoyl esters or sulfonates CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed