Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458750 | 1.00 | KCNH2 (0.49) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| SCHEMBL7614671 | 0.98 | KCNH2 (0.46) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| SCHEMBL502029 | 0.92 | KCNH2 (0.46) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| SCHEMBL4228707 | 0.83 | TP53 (0.46) | KCNH2TP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL28437803 | 0.82 | KCNH2 (0.59) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| SCHEMBL5314925 | 0.73 | KCNH2 (0.57) | KCNH2DNM1TP53SMN1; SMN2SIGMAR1 | |
| Ethylbenzene SCHEMBL798422 | 0.73 | TP53 (0.74) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| Hexadecane SCHEMBL10591100 | 0.73 | TP53 (0.74) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| Decane SCHEMBL10591097 | 0.73 | TP53 (0.74) | KCNH2DNM1MEN1KMT2AEPHX2 | |
| Ethylbenzene SCHEMBL3882350 | 0.73 | TP53 (0.74) | KCNH2DNM1MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553594-A1 | Polymeric thermoplastic materials, comprising 1,2,4-triazolidine-3,5-dione derivatives as stabilisers | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| US-5210118-A | Phenyl-3-Pyrazolidinones | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| US-5196465-A | Heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0462068-A2 | A method for stabilizing synthetic thermoplastic materials against thermal degradation | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |