SCHEMBL502029

SCHEMBL502029

CCCC[C]Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.46
TP53 P04637 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
SIGMAR1 Q99720 1/20 0.41
DNM1 Q05193 2/20 0.40
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
EPHX2 P34913 1/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7614671 0.94 KCNH2 (0.46) KCNH2TP53SMN1; SMN2SIGMAR1DNM1
SCHEMBL9458750 0.92 KCNH2 (0.49) KCNH2TP53SMN1; SMN2SIGMAR1DNM1
SCHEMBL9458307 0.92 KCNH2 (0.49) KCNH2TP53SMN1; SMN2SIGMAR1DNM1
SCHEMBL4228707 0.86 TP53 (0.46) KCNH2TP53SMN1; SMN2SIGMAR1
SCHEMBL5314925 0.81 KCNH2 (0.57) KCNH2TP53SMN1; SMN2SIGMAR1DNM1
SCHEMBL4218700 0.77 TP53 (0.50) KCNH2TP53
SCHEMBL219176 0.75 ALDH1A1 (0.53) TP53SMN1; SMN2
SCHEMBL6226882 0.75 ALDH1A1 (0.46) SMN1; SMN2SIGMAR1
Pentane SCHEMBL28982983 0.74 KCNH2 (0.46) KCNH2TP53SMN1; SMN2SIGMAR1DNM1
SCHEMBL28437803 0.74 KCNH2 (0.59) KCNH2TP53SMN1; SMN2DNM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10640641-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2020-05-05 US disclosed
US-20200062953-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2020-02-27 US disclosed
US-20180237635-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2018-08-23 US disclosed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US disclosed
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 EP disclosed
WO-2016137881-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES (US) 2016-09-01 WO disclosed
US-20160244606-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2016-08-25 US disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-8912113-B2 Compositions of a metal amidine complex and second compound, coating compositions comprising same KING INDUSTRIES, INC. (US) 2014-12-16 US disclosed
EP-2670790-A2 METHODS OF FLAME RETARDING POLYETHYLENE PROCESSED AT HIGH TEMPERATURES BASF SE (DE) 2013-12-11 EP disclosed
EP-0608198-A1 Cyclic diphenylacetonenitriles as stabilisers CIBA-GEIGY AG (CH) 1994-07-27 EP disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed
EP-0553594-A1 Polymeric thermoplastic materials, comprising 1,2,4-triazolidine-3,5-dione derivatives as stabilisers CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
US-5210118-A Phenyl-3-Pyrazolidinones CIBA-GEIGY CORPORATION (US) 1993-05-11 US disclosed
US-5196465-A Heat resistance CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
EP-0232224-B1 PIPERIDINE COMPOUNDS CIBA-GEIGY AG (CH) 1992-11-25 EP disclosed
EP-0462068-A2 A method for stabilizing synthetic thermoplastic materials against thermal degradation CIBA-GEIGY AG (CH) 1991-12-18 EP disclosed
US-5030729-A Stabilizing Polyolefins Against Oxidative, Thermal And-Or Light Induced Degradation CIBA-GEIGY CORPORATION (US) 1991-07-09 US disclosed
US-4927925-A Piperidine compounds and their use as thermal stabilizers CIBA-GEIGY CORPORATION (US) 1990-05-22 US disclosed
US-4803234-A Piperidine compounds and their use as anti-oxidative, light or thermal induced degradation agents CIBA-GEIGY CORPORATION (US) 1989-02-07 US disclosed