SCHEMBL9458337

SCHEMBL9458337

CCCCCCCOC(=O)c1ccc2cc(C(=O)OCCCCCCC)ccc2c1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
NPC1 O15118 1/20 0.67
MAPT P10636 1/20 0.67
RAB9A P51151 1/20 0.67
ESR1 P03372 5/20 0.62
AKR1C4 P17516 1/20 0.62
AKR1C3 P42330 1/20 0.62
AKR1C2 P52895 1/20 0.62
AKR1C1 Q04828 1/20 0.62
STS P08842 6/20 0.61
TSHR P16473 2/20 0.58
LMNA P02545 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
MAPK1 P28482 1/20 0.58
CYP2C19 P33261 1/20 0.58
NR1H2 P55055 1/20 0.58
RNASEL Q05823 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16632600 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL4853372 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL9458309 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL9458671 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL9458677 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL30316540 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL16632439 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL9458998 0.98 NPC1 (0.64) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL30316301 0.98 NPC1 (0.64) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL28091603 0.95 NPC1 (0.61) ALDH1A1NPC1MAPTRAB9AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5230828-A NAPHTHALENEDICARBOXYLIC ACID ESTERS HOFFMANN-LA ROCHE INC. (US) 1993-07-27 US disclosed