Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458580 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTKMT2ATDP1NPC1 | |
| SCHEMBL10798429 | 0.89 | KMT2A (0.42) | SMN1; SMN2HTTKMT2ATDP1NPC1 | |
| SCHEMBL10798435 | 0.89 | KMT2A (0.42) | SMN1; SMN2HTTKMT2ATDP1NPC1 | |
| SCHEMBL9458101 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTKMT2ATDP1NPC1 | |
| SCHEMBL9458110 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTKMT2ATDP1NPC1 | |
| SCHEMBL10799197 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL10799191 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL9257519 | 0.86 | KMT2A (0.44) | SMN1; SMN2HTTKMT2ATDP1F2 | |
| SCHEMBL9257522 | 0.86 | KMT2A (0.44) | SMN1; SMN2HTTKMT2ATDP1F2 | |
| SCHEMBL9250383 | 0.86 | KMT2A (0.44) | SMN1; SMN2HTTKMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238602-A | Electrooptical cells | HOFFMANN LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |