Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.56 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9137327 | 0.99 | AGTR1 (0.55) | AGTR1AGTR2LIPE | |
| SCHEMBL4767008 | 0.84 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9177090 | 0.78 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL4764548 | 0.76 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9178138 | 0.75 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9181093 | 0.75 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9141699 | 0.75 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL31425607 | 0.74 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL5538132 | 0.74 | KDM4E (0.51) | AGTR1AGTR2 | |
| SCHEMBL9182577 | 0.74 | KDM4E (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | claimed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |