Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 11/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 2/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137529 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL6851992 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL13152832 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL10393880 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL13150977 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL17714999 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL137530 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL17726095 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL11702370 | 0.93 | HIF1A (0.81) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL142385 | 0.91 | KMT2A (1.00) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225335-A | Enzymatic dehydrogenation | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |