Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458316 | 0.95 | HSP90AA1 (0.43) | HSP90AA1NPSR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL9457894 | 0.89 | ALDH1A1 (0.44) | HSP90AA1NPSR1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL11547359 | 0.88 | HSP90AA1 (0.48) | HSP90AA1NPSR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL9457977 | 0.84 | KDM4E (0.46) | HSP90AA1NPSR1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL11542005 | 0.84 | ALDH1A1 (0.48) | HSP90AA1NPSR1CYP3A4CYP19A1TSHR | |
| SCHEMBL11544728 | 0.80 | HSP90AA1 (0.61) | HSP90AA1NPSR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11541071 | 0.80 | CYP3A4 (0.50) | HSP90AA1NPSR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11547879 | 0.80 | GAA (0.49) | HSP90AA1NPSR1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL11541496 | 0.79 | ALDH1A1 (0.50) | HSP90AA1NPSR1CYP3A4CYP19A1TSHR | |
| SCHEMBL9458451 | 0.79 | CACNA1B (0.42) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065485-B1 | ARYLPHENYL ETHER DERIVATIVES AS MICROBICIDES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| EP-0065485-A2 | Arylphenyl ether derivatives as microbicides, process for their preparation and their application | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | claimed |
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0065485-A2 | Arylphenyl ether derivatives as microbicides, process for their preparation and their application | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | disclosed |