SCHEMBL9458902

SCHEMBL9458902

CCCCCCc1cc(N(C)CC)ccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.49
HPSE Q9Y251 3/20 0.47
PPARG P37231 2/20 0.46
KAT8 Q9H7Z6 4/20 0.46
RARB P10826 3/20 0.45
RARA P10276 1/20 0.45
RARG P13631 1/20 0.45
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6247855 0.89 PPARA (0.51) PPARAHPSEPPARGKAT8RARB
SCHEMBL4889679 0.89 PPARA (0.51) PPARAHPSEPPARGKAT8RARB
SCHEMBL9517713 0.89 PPARA (0.51) PPARAHPSEPPARGKAT8RARB
SCHEMBL38613 0.89 PPARA (0.51) PPARAHPSEPPARGKAT8RARB
SCHEMBL480460 0.87 PPARA (0.49) PPARAHPSEPPARGKAT8RARB
SCHEMBL7750610 0.86 PPARA (0.49) PPARAHPSEPPARGKAT8RARB
SCHEMBL9161263 0.86 SMN1; SMN2 (0.50) PPARAHPSEPPARGKAT8RARB
SCHEMBL4914947 0.82 GABRP (0.49) PPARAHPSEPPARGKAT8RARB
SCHEMBL3305470 0.82 SLC16A3 (0.43) PPARAHPSEPPARGKAT8RARB
SCHEMBL6250083 0.82 F7 (0.51) PPARAHPSEPPARGKAT8BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5230874-A Ultraviolet radiation absorbers THE PROCTER & GAMBLE COMPANY (US) 1993-07-27 US disclosed
US-5229107-A Sunscreen agents, sunscreen compositions and methods for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1993-07-20 US disclosed
US-5229106-A Sunscreen agents, sunscreen compositions and method for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1993-07-20 US disclosed
US-5160731-A Unsaturated ketones containing ester or amide groups, UVA and UVB absorbers THE PROCTER & GAMBLE COMPANY (US) 1992-11-03 US disclosed
EP-0255157-B1 NOVEL SUNSCREEN AGENTS, SUNSCREEN COMPOSITIONS AND METHODS FOR PREVENTING SUNBURN THE PROCTER & GAMBLE COMPANY (US) 1992-08-12 EP disclosed
US-5041282-A Topical application of sunscreen agent THE PROCTER & GAMBLE COMPANY (US) 1991-08-20 US disclosed
US-4999186-A P-aminobenzoic acid derivatives; chromogens THE PROCTER & GAMBLE COMPANY (US) 1991-03-12 US disclosed
EP-0255157-A2 Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1988-02-03 EP disclosed