Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696055 | 0.71 | MAPT (0.35) | CA12CA7CA14MAPT | |
| SCHEMBL28223057 | 0.71 | CA12 (0.32) | CA12CA7CA14MAPT | |
| SCHEMBL27613812 | 0.71 | CA12 (0.33) | CA12CA7CA14MAPT | |
| SCHEMBL27810211 | 0.71 | CA12 (0.32) | CA12CA7CA14MAPT | |
| SCHEMBL9646368 | 0.67 | — | — | |
| SCHEMBL272485 | 0.67 | SMN1; SMN2 (0.37) | MAPT | |
| SCHEMBL2754289 | 0.66 | MAPT (0.33) | MAPT | |
| SCHEMBL8506062 | 0.64 | — | — | |
| SCHEMBL28971983 | 0.64 | MGLL (0.40) | CA12CA7CA14MAPT | |
| SCHEMBL28001517 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262400-A | Antiparasitic and anthelmintic | MERCK & CO., INC. (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0519731-A1 | 4a-Substituted avermectin derivatives | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | disclosed |