Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459772 | 1.00 | CHRM5 (0.42) | CHRM5ADRA2CCHRNA7PKMSLC18A3 | |
| SCHEMBL9458795 | 0.77 | CHRM5 (0.42) | CHRM5ADRA2CCHRNA7 | |
| SCHEMBL9459207 | 0.74 | CHRNA7 (0.43) | CHRM5ADRA2CCHRNA7 | |
| SCHEMBL1862738 | 0.71 | CHRNA7 (0.42) | CHRNA7PKMSLC18A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1014986 | 0.69 | CHRNA7 (0.41) | CHRNA7PKMSLC18A3 | |
| SCHEMBL5615403 | 0.67 | CHRNA7 (0.40) | CHRNA7SLC18A3MEN1KMT2A | |
| SCHEMBL4901703 | 0.67 | CHRNA7 (0.40) | CHRNA7SLC18A3 | |
| SCHEMBL9667433 | 0.65 | CHRNA7 (0.39) | CHRNA7SLC18A3 | |
| SCHEMBL714926 | 0.63 | LSS (0.41) | CHRNA7 | |
| SCHEMBL714927 | 0.63 | LSS (0.41) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273972-A | [(2-diakylaminomethyl)-3-quinuclidinyl]-benzamides and benzoates | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |