SCHEMBL9458795

SCHEMBL9458795

NC1C2CCN(CC2)C1CN1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.42
ADRA2C P18825 1/20 0.42
CHRNA7 P36544 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9459207 0.98 CHRNA7 (0.43) CHRM5ADRA2CCHRNA7
SCHEMBL9458901 0.81 CHRNA7 (0.40) CHRNA7
SCHEMBL9459772 0.77 CHRM5 (0.42) CHRM5ADRA2CCHRNA7
SCHEMBL9459185 0.77 CHRM5 (0.42) CHRM5ADRA2CCHRNA7
Hydrochloric Acid SCHEMBL9279446 0.69 CHRNA7 (0.41) CHRNA7
SCHEMBL9459170 0.67 CHRNA7 (0.40) CHRNA7
SCHEMBL28554136 0.65 CHRNA7 (0.39) CHRNA7
SCHEMBL28554134 0.65 CHRNA7 (0.39) CHRNA7
SCHEMBL28563561 0.65 CHRNA7 (0.39) CHRNA7
SCHEMBL25856195 0.63 CHRM5 (0.53) CHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5273972-A [(2-diakylaminomethyl)-3-quinuclidinyl]-benzamides and benzoates A. H. ROBINS COMPANY, INCORPORATED (US) 1993-12-28 US disclosed