Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459669 | 1.00 | GMNN (0.44) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9158118 | 0.93 | GMNN (0.52) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9459762 | 0.93 | GMNN (0.52) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9459614 | 0.92 | GMNN (0.44) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9459172 | 0.92 | GMNN (0.44) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9458989 | 0.91 | GMNN (0.46) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9459495 | 0.91 | GMNN (0.46) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9459297 | 0.91 | PTGS2 (0.38) | — | |
| SCHEMBL9459269 | 0.91 | PTGS2 (0.38) | — | |
| SCHEMBL9460209 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234918-A | For cardiovascular, respiratory, carcinogenic and inflammatory disorders | AMERICAN CYANAMID COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5215975-A | Certain hydroxy-phosphinyl-oxy-phenyl methyl-thiazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1993-06-01 | — | — | US | disclosed |