Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 17/20 | 0.59 |
| ▸ | EDNRA | P25101 | 17/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095204 | 1.00 | EDNRB (0.59) | EDNRBEDNRAPPARA | |
| SCHEMBL14298981 | 0.90 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL9459527 | 0.88 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL12096276 | 0.88 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL14244959 | 0.87 | EDNRB (0.49) | EDNRBEDNRA | |
| SCHEMBL9723480 | 0.86 | PPARA (0.48) | EDNRBEDNRAPPARA | |
| SCHEMBL12095220 | 0.84 | EDNRB (0.49) | EDNRBEDNRA | |
| SCHEMBL12095212 | 0.83 | EDNRB (0.49) | EDNRBEDNRA | |
| SCHEMBL9755161 | 0.82 | EDNRB (0.47) | EDNRBEDNRA | |
| SCHEMBL9723559 | 0.81 | EDNRB (0.55) | EDNRBEDNRAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573907-B2 | 2, 4-pyrimidine derivatives and use thereof | SNU R&DB FOUNDATION (KR) | 2017-02-21 | — | — | US | claimed |
| US-20120322802-A1 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-12-20 | — | — | US | claimed |
| EP-2497768-A2 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | SNU R&DB Foundation (KR) | 2012-09-12 | — | — | EP | claimed |
| JP-1301668-A | — | — | None | — | — | JP | disclosed |
| US-9573907-B2 | 2, 4-pyrimidine derivatives and use thereof | SNU R&DB FOUNDATION (KR) | 2017-02-21 | — | — | US | disclosed |
| US-9573907-B2 | 2, 4-pyrimidine derivatives and use thereof | SNU R&DB FOUNDATION (KR) | 2017-02-21 | — | — | US | disclosed |
| US-9573907-B2 | 2, 4-pyrimidine derivatives and use thereof | SNU R&DB FOUNDATION (KR) | 2017-02-21 | — | — | US | disclosed |
| EP-2497768-B1 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | SNU R&DB FOUNDATION (KR) | 2016-04-20 | — | — | EP | disclosed |
| US-20120322802-A1 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-12-20 | — | — | US | disclosed |
| US-20120322802-A1 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-12-20 | — | — | US | disclosed |
| US-20120322802-A1 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-12-20 | — | — | US | disclosed |
| EP-2497768-A2 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | SNU R&DB Foundation (KR) | 2012-09-12 | — | — | EP | disclosed |
| US-5270289-A | Herbicidal dimethoxy pyrimidinyloxy-fluorinated acids and salts | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |
| US-5139563-A | HERBICIDAL COMPOUNDS | SHELL RESEARCH LIMITED (GB) | 1992-08-18 | — | — | US | disclosed |
| EP-0409368-A2 | Substituted alfa pyrimidinyloxy carboxylic acid derivatives, process for their preparation and their use as an agent with herbicidal, fungicidal and plantgrowth regulating activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-23 | — | — | EP | disclosed |
| EP-0400741-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-12-05 | — | — | EP | disclosed |
| JP-H01301668-A | MANDELIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEM IND CO LTD | 1989-12-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322802-A1 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF | LY96, AIMP1, NLRP1 | EDNRB 4586/4885EDNRA 4633/4885PPARA 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.