Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | EDNRB | P24530 | 5/20 | 0.43 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095204 | 0.86 | EDNRB (0.59) | PPARAEDNRBEDNRA | |
| SCHEMBL9459285 | 0.86 | EDNRB (0.59) | PPARAEDNRBEDNRA | |
| SCHEMBL9723448 | 0.83 | ALDH1A1 (0.48) | PPARAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9723559 | 0.82 | EDNRB (0.55) | PPARAKDM4EALDH1A1KMT2APPARG | |
| SCHEMBL7698955 | 0.77 | PPARA (0.45) | PPARAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11397979 | 0.76 | KMT2A (0.64) | PPARAALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL21881560 | 0.76 | MEN1 (0.58) | PPARAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5944601 | 0.76 | MEN1 (0.58) | PPARAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14298981 | 0.75 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL12096276 | 0.74 | EDNRB (0.53) | KMT2AEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139563-A | HERBICIDAL COMPOUNDS | SHELL RESEARCH LIMITED (GB) | 1992-08-18 | — | — | US | disclosed |
| EP-0400741-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-12-05 | — | — | EP | disclosed |