Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084247 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EGAAADORA3 | |
| SCHEMBL9374377 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EADORA3ADORA1 | |
| SCHEMBL9051760 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL13685316 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL9573163 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EGAAADORA3 | |
| SCHEMBL10879106 | 0.79 | MEN1 (0.59) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL10880545 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL9408723 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGAAADORA3 | |
| SCHEMBL6641067 | 0.74 | POLB (0.60) | ALDH1A1KDM4EGAAADORA3ADORA1 | |
| SCHEMBL9408738 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270289-A | Herbicidal dimethoxy pyrimidinyloxy-fluorinated acids and salts | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0571856-A1 | Pyrimidinylthioacrylic acid derivatives useful as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-5089044-A | SUBSTITUTED PYRIMIDINYLOXY(THIO)- AND TRIAZINYLOXY (THIO)ACRYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES, FUNGICIDES AND PLANT GROWTH REGULATORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |