Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.35 |
| ▸ | UGT2B17 | O75795 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460882 | 1.00 | EPHX1 (0.38) | EPHX1L3MBTL1CYP1A2CYP2D6GBA1 | |
| SCHEMBL9460794 | 1.00 | EPHX1 (0.38) | EPHX1L3MBTL1CYP1A2CYP2D6GBA1 | |
| SCHEMBL3909948 | 0.78 | GAA (0.41) | EPHX1L3MBTL1CYP1A2CYP2D6HIF1A | |
| SCHEMBL5207895 | 0.78 | DPP4 (0.37) | L3MBTL1CYP1A2CYP2D6CYP3A4TSHR | |
| SCHEMBL2254431 | 0.78 | L3MBTL1 (0.33) | L3MBTL1CYP1A2CYP2D6HIF1ACYP3A4 | |
| SCHEMBL2202292 | 0.74 | GAA (0.37) | L3MBTL1CYP2D6TSHRLMNAGAA | |
| SCHEMBL8705439 | 0.70 | KDM4E (0.53) | EPHX1L3MBTL1CYP1A2CYP2D6HIF1A | |
| SCHEMBL3310267 | 0.70 | CYP1A2 (0.53) | EPHX1L3MBTL1CYP1A2CYP2D6HIF1A | |
| SCHEMBL4676513 | 0.69 | CYP1A2 (0.49) | EPHX1L3MBTL1CYP1A2CYP2D6GBA1 | |
| SCHEMBL11572938 | 0.69 | GAA (0.33) | L3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079359-A | Ligand to metals with Lewis acidity, catalyst for assymetric synthesis | TOSOH CORPORATION (JP) | 1992-01-07 | — | — | US | claimed |
| US-5212311-A | Catalysts | TOSOH CORPORATION (JP) | 1993-05-18 | — | — | US | disclosed |
| US-5079359-A | Ligand to metals with Lewis acidity, catalyst for assymetric synthesis | TOSOH CORPORATION (JP) | 1992-01-07 | — | — | US | disclosed |