Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571490 | 0.81 | — | — | |
| SCHEMBL1701907 | 0.78 | — | — | |
| SCHEMBL13411366 | 0.75 | — | — | |
| SCHEMBL10660072 | 0.75 | — | — | |
| SCHEMBL124325 | 0.74 | OPRM1 (0.35) | ALDH1A1 | |
| SCHEMBL17016727 | 0.73 | TRPV1 (0.31) | ALDH1A1 | |
| SCHEMBL17131451 | 0.73 | TRPV1 (0.31) | ALDH1A1 | |
| SCHEMBL17016728 | 0.73 | TRPV1 (0.31) | ALDH1A1 | |
| SCHEMBL9359638 | 0.72 | TSHR (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8206007 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294525-B1 | HYDROXYL-FUNCTIONAL DISILOXANES AND POLYSILOXANE OLIGOMERS | Th. Goldschmidt AG (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0294525-A1 | Hydroxyl-functional disiloxanes and polysiloxane oligomers | Th. Goldschmidt AG (DE) | 1988-12-14 | — | — | EP | disclosed |
| US-4689383-A | Hydroxyl-functional disiloxanes and polysiloxane oligomers | THORATEC LABORATORIES CORP. (US) | 1987-08-25 | — | — | US | disclosed |