Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PYGM | P11217 | 4/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656957 | 0.85 | ALDH1A1 (0.49) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL8630248 | 0.85 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL9460697 | 0.82 | ALDH1A1 (0.45) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL9460965 | 0.81 | ALDH1A1 (0.51) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL29401261 | 0.80 | POLB (0.58) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL260857 | 0.80 | POLB (0.58) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL21437004 | 0.79 | POLB (0.56) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL21437005 | 0.79 | POLB (0.56) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| SCHEMBL9847757 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBTDP1DUSP3PTPN5 | |
| Water SCHEMBL3777569 | 0.79 | POLB (0.56) | ALDH1A1POLBTDP1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189137-A | Method for preparing a high molecular weight polyethermide polymer in a dual solvent system | GENERAL ELECTRIC COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| US-4769476-A | POLYIMIDE MONOMERS | GENERAL ELECTRIC COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0217267-A2 | Bis(dialkyl aromatic ether anhydride) and polymers obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4650850-A | IMPROVED HEAT DISTORTION TEMPERATURES | GENERAL ELECTRIC COMPANY (US) | 1987-03-17 | — | — | US | disclosed |