Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463417 | 0.88 | PRCP (0.50) | SLC6A2SLC6A4SLC6A3PRCPCHRM3 | |
| SCHEMBL9463649 | 0.86 | PRCP (0.43) | SLC6A2SLC6A4SLC6A3PRCPHDAC8 | |
| SCHEMBL9463843 | 0.86 | PRCP (0.40) | PRCPCHRM3HTR2AHTR2CHTR2B | |
| SCHEMBL9463711 | 0.85 | HTR2A (0.38) | SLC6A2SLC6A4SLC6A3PRCPKMT2A | |
| SCHEMBL9463729 | 0.83 | HDAC1 (0.48) | SLC6A2SLC6A4SLC6A3PRCPGAA | |
| SCHEMBL9851315 | 0.73 | MAPT (0.49) | SLC6A2SLC6A4SLC6A3PRCPKMT2A | |
| SCHEMBL9463190 | 0.73 | MAPT (0.49) | SLC6A2SLC6A4SLC6A3PRCPKMT2A | |
| SCHEMBL9465105 | 0.71 | MAPT (0.35) | SLC6A2SLC6A4SLC6A3PRCPKMT2A | |
| SCHEMBL14417391 | 0.70 | PRCP (0.78) | PRCPCHRM3HDAC8 | |
| SCHEMBL9464110 | 0.70 | PRCP (0.37) | SLC6A2SLC6A4SLC6A3PRCPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264436-A | Alpha-adrenoceptors antagonist, hypotensive agents or antidiabetic agents | BEECHAM GROUP P.L.C. (GB) | 1993-11-23 | — | — | US | disclosed |
| EP-0275639-B1 | N-SUBSTITUTED CYCLIC AMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1992-07-15 | — | — | EP | disclosed |
| US-5077299-A | Glaucoma, antidepressants, anticoagulants, hypotensive agents | BEECHAM GROUP P.L.C. (GB) | 1991-12-31 | — | — | US | disclosed |
| US-4918083-A | 4,5 Dihydroimidazole compounds which have useful pharmaceutical utility | BEECHAM GROUP P.L.C. (GB) | 1990-04-17 | — | — | US | disclosed |
| EP-0275639-A1 | N-substituted cyclic amides, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-07-27 | — | — | EP | disclosed |