SCHEMBL9463252

SCHEMBL9463252

O=C(O)c1cc(Cc2ccccc2)cc(C2CCCCC2)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.58
PTPN2 P17706 2/20 0.58
PTPN6 P29350 2/20 0.58
HNF4A P41235 1/20 0.50
HMGB1 P09429 2/20 0.45
CXCL12 P48061 2/20 0.45
ACMSD Q8TDX5 3/20 0.44
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
KLKB1 P03952 1/20 0.41
CTSB P07858 1/20 0.41
MMP9 P14780 1/20 0.41
DNMT1 P26358 1/20 0.41
DNMT3B Q9UBC3 1/20 0.41
DNMT3L Q9UJW3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9247116 0.81 KDM4E (0.46) PTPN1HMGB1CXCL12ACMSDKDM4E
SCHEMBL9249706 0.78 PTPN1 (0.59) PTPN1PTPN2PTPN6HNF4AHMGB1
SCHEMBL9250275 0.78 PTPN1 (0.55) PTPN1PTPN2PTPN6HNF4AACMSD
SCHEMBL11553453 0.78 HSD17B10 (0.54) HMGB1CXCL12ACMSDKDM4EMEN1
SCHEMBL11614576 0.78 NUDT1 (0.49) PTPN2ACMSDKDM4EMEN1MAPT
SCHEMBL22103820 0.77 NUDT1 (0.61) HNF4AACMSDKDM4EMEN1KMT2A
SCHEMBL11625563 0.77 NUDT1 (0.46) PTPN2KDM4EMEN1MAPTKMT2A
SCHEMBL11776420 0.76 KDM4E (0.51) ACMSDKDM4EMEN1MAPTKMT2A
SCHEMBL11773551 0.76 KDM4E (0.51) ACMSDKDM4EMEN1MAPTKMT2A
SCHEMBL11777205 0.75 KAT8 (0.52) KDM4EMEN1MAPTKMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202722-A Image-forming system BROTHER KOGYO KABUSHIKI KAISHA (JP) 1993-04-13 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed