Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.67 |
| ▸ | PGR | P06401 | 6/20 | 0.67 |
| ▸ | SHBG | P04278 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126888 | 1.00 | NR3C1 (0.67) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL9126883 | 1.00 | NR3C1 (0.67) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL18885151 | 0.87 | HIF1A (0.77) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL8342173 | 0.87 | HIF1A (0.77) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL6804668 | 0.87 | HIF1A (0.77) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL8342176 | 0.87 | HIF1A (0.77) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL9650590 | 0.87 | HIF1A (0.77) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL11646406 | 0.87 | HIF1A (0.79) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL11646411 | 0.87 | HIF1A (0.79) | NR3C1PGRSHBGALDH1A1ADRA1A | |
| SCHEMBL11871735 | 0.86 | NR3C1 (0.70) | NR3C1PGRSHBGALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236912-A | Treating prostate hyperplasia and carcinoma | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |