Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 7/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991763 | 0.98 | THRB (0.70) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL3103061 | 0.96 | TSHR (0.71) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL14706828 | 0.96 | THRB (0.68) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL8507839 | 0.94 | TSHR (0.74) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL26735154 | 0.94 | TSHR (0.74) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL9568827 | 0.94 | THRB (0.70) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL2742411 | 0.94 | THRB (0.70) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL5446483 | 0.94 | TSHR (0.74) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL874556 | 0.93 | TSHR (0.79) | THRBTSHRHTTPOLBAPEX1 | |
| SCHEMBL19077763 | 0.93 | TSHR (0.79) | THRBTSHRHTTPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980510-B1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-1803555-B1 | Ink composition, inkjet recording method, producing method of planographic printing plate, and planographic printing plate | FUJIFILM CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| EP-0368657-B1 | DENTAL RESTORATIVE MATERIAL | KURARAY CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5192815-A | Ultrafine filler, silane coupling agent, acrylic ester monomer | KURARAY CO., LTD. (JP) | 1993-03-09 | — | — | US | disclosed |
| EP-0368657-A2 | Dental restorative material | KURARAY CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |