Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464186 | 1.00 | HCAR2 (0.48) | HCAR2TP53TSHRPGRALKBH5 | |
| SCHEMBL7043535 | 0.84 | HCAR2 (0.53) | HCAR2PGRALKBH5ADRA2AADRA2B | |
| SCHEMBL7043537 | 0.78 | HCAR2 (0.45) | HCAR2PGRALKBH5ADRA2AADRA2B | |
| SCHEMBL9464854 | 0.74 | HCAR2 (0.50) | HCAR2TP53TSHRALDH1A1TDP1 | |
| SCHEMBL9464820 | 0.74 | HCAR2 (0.50) | HCAR2TP53TSHRALDH1A1TDP1 | |
| SCHEMBL9464199 | 0.73 | HCAR2 (0.54) | HCAR2TP53TSHRPGRALKBH5 | |
| SCHEMBL7044308 | 0.69 | ALDH1A1 (0.47) | HCAR2ALDH1A1LMNAMEN1MAPT | |
| SCHEMBL13710706 | 0.69 | CES1 (0.48) | TP53TSHRPGRALKBH5ADRA2A | |
| SCHEMBL28803484 | 0.67 | HCAR2 (0.69) | HCAR2ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL27534212 | 0.67 | HCAR2 (0.69) | HCAR2ALDH1A1MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177249-A | Dicarboxylic acid monoester plus epoxide | CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) | 1993-01-05 | — | — | US | disclosed |