SCHEMBL9464267

SCHEMBL9464267

O=C(OCC[n+]1ccccc1)c1ccc2ccccc2c1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.46
DRD3 P35462 1/20 0.45
MAPT P10636 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HTT P42858 1/20 0.41
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
PTPN1 P18031 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
NR1H4 Q96RI1 1/20 0.37
KMT2A Q03164 3/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 2/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 2/20 0.37
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9586204 0.92 HRH3 (0.52) HRH3DRD3MAPTKDM4EHTT
SCHEMBL8968434 0.86 TDP1 (0.51) KDM4ETDP1KMT2ANPC1ALDH1A1
SCHEMBL9540331 0.77 TDP1 (0.61) TDP1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL27691343 0.77 HRH3 (0.64) HRH3DRD3MAPTKDM4EHTT
SCHEMBL9463800 0.76 ALDH1A1 (0.41) KDM4EPOLBALDH1A1
Bromide SCHEMBL9463996 0.75 TDP1 (0.59) TDP1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL4570310 0.74 HRH3 (0.66) HRH3DRD3MAPTKDM4EHTT
SCHEMBL16606218 0.72 HRH3 (0.59) HRH3DRD3MAPTKDM4EHTT
SCHEMBL9463784 0.72 POLB (0.46) MAPTHTTADRB2ADRB1ADRB3
SCHEMBL9397888 0.72 ESR1 (0.65) HRH3DRD3MAPTKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5212035-A Ester containing pyridinium group EASTMAN KODAK COMPANY (US) 1993-05-18 US claimed
US-5196539-A Electrography EASTMAN KODAK COMPANY (US) 1993-03-23 US claimed
WO-1993002400-A1 TONERS AND DEVELOPERS CONTAINING ESTER-CONTAINING QUATERNARY PYRIDINIUM SALTS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1993-02-04 WO claimed
WO-1993002054-A1 ESTER-CONTAINING QUATERNARY PYRIDINIUM SALTS EASTMAN KODAK COMPANY (US) 1993-02-04 WO claimed
US-5212035-A Ester containing pyridinium group EASTMAN KODAK COMPANY (US) 1993-05-18 US disclosed
US-5196539-A Electrography EASTMAN KODAK COMPANY (US) 1993-03-23 US disclosed
WO-1993002400-A1 TONERS AND DEVELOPERS CONTAINING ESTER-CONTAINING QUATERNARY PYRIDINIUM SALTS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1993-02-04 WO disclosed