Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829675 | 0.96 | — | — | |
| SCHEMBL550510 | 0.96 | CYP2C9 (0.39) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL21965258 | 0.96 | MAPK1 (0.38) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL551635 | 0.92 | CYP2C9 (0.37) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| Hydrochloric Acid SCHEMBL1819609 | 0.92 | CYP2C9 (0.37) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL7848795 | 0.92 | CYP2C9 (0.37) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL550147 | 0.92 | CYP2C9 (0.37) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL16878579 | 0.92 | MAPK1 (0.36) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL550429 | 0.91 | — | — | |
| SCHEMBL14545648 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244899-A | Azabicycloalkyl and azatricycloalkyl amides used to treat inflammation, allergy, asthma and skin disorders | G. D. SEARLE AND CO. (US) | 1993-09-14 | — | — | US | claimed |
| US-5198435-A | Antiinflammatory, antiallergen | G. D. SEARLE & CO. (US) | 1993-03-30 | — | — | US | claimed |
| US-20240287383-A1 | SILICON-ETCHANT COMPOSITION AND METHOD OF FORMING PATTERN USING THE SAME | DONGWOO FINE-CHEM CO., LTD. (KR) | 2024-08-29 | — | — | US | disclosed |
| CN-118530724-A | Silicon etchant composition and method of forming pattern using the same | 东友精细化工有限公司 | 2024-08-23 | — | — | CN | disclosed |
| US-5244899-A | Azabicycloalkyl and azatricycloalkyl amides used to treat inflammation, allergy, asthma and skin disorders | G. D. SEARLE AND CO. (US) | 1993-09-14 | — | — | US | disclosed |
| US-5198435-A | Antiinflammatory, antiallergen | G. D. SEARLE & CO. (US) | 1993-03-30 | — | — | US | disclosed |
| US-5157053-A | Bicycloalky, tricycloalkyl, azabicycloalkyl, and azatricycloalkyl thio amides used to treat inflammation, allergy, asthma and skin disorders | G. D. SEARLE & CO. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5019597-A | Antiinflammatory Agents, Antiallergens | G. D. SEARLE & CO. (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0190684-A2 | Bicycloalkyl, tricycloalkyl, azabicycloalkyl and azatricycloalkyl amides | G.D. Searle & Co. (US) | 1986-08-13 | — | — | EP | disclosed |